Do You Suffer from Endocannabinoid Deficiency?
endocannabinoid deficiency

Endocannabinoid Deficiency could be the key to understanding why people suffer from so many ailments. We are beginning to understand the importance of the endocannabinoid system within the individual and so, we're discovering new aspects of human health.

Could you be Suffering from Clinical Endocannabinoid Deficiency?

Have you been trying everything but nothing seems to work? You could be suffering from Clinical Endocannabinoid Deficiency (CED). It is not a fabricated excuse to indulge in Cannabis, because even though you might not be a smoker or consumer, you could still be Endocannabinoid Deficient.

Any deficiency or excess for that matter can cause loads of problems. The only moment when we find ourselves in perfect health is when there is homeostasis. A perfect balance which induces a perfect state of well being.

What is Endocannabinoid Deficiency?

endocannabinoid deficiency
How does it affect you? Endocannabinoid deficiency is just that, a lack of endocannabinoids.  The word can be broken down to endo (internal or within) and cannabinoid. They are neurotransmitters that function in both the central and peripheral nervous systems binding to cannabinoid receptors and receptor proteins. The Endocannabinoid system in fact is a homeostatic regulator in mammals helping the body to regulate all other systems.

Endocannabinoid Deficiency Syndrome is thus something like an umbrella term that includes a group of illnesses like irritable bowel syndrome, migraine and fibromyalgia. Many scientists believe that a lack of endocannabinoids is the root of many illnesses and evidence suggests that endocannabinoids play a major role in insulin sensitivity, inflammation and fat and energy metabolism.

All mammals synthesize endocannabinoids naturally. The two endocannabinoids, anandamide and 2-AG, bind to specific endocannabinoid receptors. Anandamide locks onto CB1 receptors and 2-AG locks onto CB2 receptors. The cannabinoids in Cannabis also lock onto these receptors.


How do you Know if you are CED?

There are a number of reasons that could cause CED from Genetic, Congenital causes (from birth), and injury and to the progress of another disease.  The most common evidence to conclude that CED is problematic is when a person suffers from fibromyalgia, irritable bowel syndrome and migraine. Often a person goes through extensive negative diagnosis and elevated anxiety and depression. They often are to believe that their problems are of psychosomatic origin and are labeled as a wastebasket diagnosis.

Symptoms of feeling tired, forgetful and achy could all indicate Endocannabinoid deficiency. Your mood can also change constantly and your metabolism and immune system show signs of imbalance.

Endocannabinoid Deficiency


The endocannabinoid system is the biggest neurotransmitter in the body and many important signaling functions are helped by it. When there is a deficiency, signaling fails to function on the proper levels.

Four distinct signs indicate that the Endocannabinoid system is disrupted:

  • Too many enzymes interrupting endocannabinoids
  • Insufficient synthesized endocannabinoids
  • Insufficient signaling between receptors and endocannabinoids
  • Not enough receptors

How many diseases can be a direct result of CED?  Apart from those mentioned above, neonatal failure to thrive, cystic fibrosis and causalgia (severe burning pain) could result from CED. Phantom limb pain, glaucoma, infantile colic and repetitive miscarriages are also present. Bipolar disease and PTSD can also be included and the list goes on.

Cannabinoids in Cannabis can play a vital role in improving Endocannabinoid Deficiency. It could bring relief and has already been proved to do so on all of the above mentioned illnesses. If you struggle with insomnia, depression, anxiety, chronic pain and inflammation, it might be wise to boost you cannabinoid intake.